Diacerein

1.Diacerein 2.CAS:13739-02-1 3.Quality:98% 4.Document:DMF 5.Use:Induction cartilage formation, has anti-inflammatory

4.Certificate Of Analysis:

ITEMS	STANDARDS
APPEARANCE	YELLOW CRYSTALLINE POWDER
SOLUBILITY	SOLUBLE IN DMSO, SPARING SOLUBLE IN DMAC. PRACTICALLY INSOLUBLE IN METHANOL, ETHANOL, ACETONITRILE AND WATER.
IDENTIFICATION	A: IR ABSORPTION SPECTRUM COMPLIES WITH REFERENCE STANDARD. B: ADD 1mol/L SODIUM HYDROXIDE TO SAMPLE SOLUTION OF DMAC, THEN TURN RED. C: IN ASSAY TEST RETENTION TIME OF MAIN PEAK OF SAMPLE SOLUTION COMPLIES WITH THAT OF REFERENCE SOLUTION.
pH	4.5~6.0
LOSS ON DRYING	≤0.5%
RESIDUE ON IGNITION	≤0.20%
HEAVY METALS	≤20ppm
RELATED SUBSTANCES	INDIVIDUAL IMPURITY: ≤0.5% TOTAL IMPURITIES: ≤1.0%
ASSAY(CALCULATED ON DRIED BASIS)	98.0% - 102.0%
CONCLUSION		COMPILES WITH THE ENTERPRISE STANDARD

5.Application:

Diacerein (INN), also known as diacetylrhein, is a drug used in the treatment of osteoarthritis. It works by inhibiting interleukin-1.

A 2005 Cochrane review found diacerein to be slightly, but significantly, more effective than placebo in diacerein has a small effect in improving pain and slowing the progress of osteoarthritis (in the hip).

6.Advantages:

(1) 25 year experience in pharmaceutical and botanical industry

(2) ISO9001:2008 certificated company

(3) stable business relations with most of the GMP sources in China

(4) Fischer Chemicals AG China office

 

7.Hot items:

γ-PGA(Gmma-poly-glutamic)   90%~92%

Chondroitin sulfate sodium USP33/EP7

Hyaluronic acid             95%min

Coenzyme Q10             USP33/EP7

Beta Carotene       10% CWS,20%TAB,30%OIL

Guaiazulene               99.5%

Diacerein                   98%

 

 

Diacerein